Type of Injection: Subcutaneous

Frequency of Injection: Weekly (or as directed by your provider)

Optimal Storage: Refrigeration

BUD: Up to 6 months on average

Information on Tirzepatide 

Information on B12

CUSTOMIZABLE DOSING PLAN

Recommended Dosing Schedule for Initiation of Treatment:

2mg once weekly for 2 weeks

4mg once weekly for 4 weeks (you should remain at this dose longer if you are losing weight consistently)

6mg once weekly for 3 weeks

Recommended Dosing Titration:

Increase by 2mg every 3-4 weeks as needed to a maximum dose of 14mg/week. If you have adequate appetite suppression at your current dose, you do not need to continue to increase. If you are sensitive to the medication or are experiencing any side effects, do not increase your dose. If you had sensitivities to the medication during any point of treatment, you can increase by only 1mg at a time if desired.

Below are the units you should administer based on the dose you are trying to achieve. The traditional dosing schedule doses are highlighted in purple.

10 mg/mL Concentration (each mL contains 500mcg of B12)

1mg = 10 units

2mg = 20 units

2.5mg = 25 units

3mg = 30 units

4mg = 40 units

5mg = 50 units

6mg = 60 units

7mg = 70 units

7.5mg = 75 units

8mg = 80 units

9mg = 90 units

10mg = 100 units

11mg = 110 units (1.1mL)

12mg = 120 units (1.2mL)

12.5mg = 125 units (1.25mL)

13mg = 130 units (1.3mL)

14mg = 140 units (1.4mL)

15mg = 150 units  (1.5mL)

TIER 1 | 40mg total

• 9 week supply for those initiating treatment, 10 week supply at 4mg/week

• Traditional Dosing: 8 week supply at 5mg/week

• supplied in two 2mL vials at a concentration of 10mg/mL

TIER 2 | 60mg total

• Custom Dosing: 10 week supply at 6mg/week

• Traditional Dosing: 8 week supply at 7.5mg/week

• supplied in three 2mL vials at a concentration of 10mg/mL

TIER 3 | 80mg total

• Custom Dosing: 10 week supply at 8mg/week, 8 week supply at 10mg/week

• Traditional Dosing: 8 week supply at 10mg/week

• supplied in four 2mL vials at a concentration of 10mg/mL

TIER 4 | 120mg total

• Custom dosing: 10 week supply at 12mg/week, 8 week supply at 14mg/week

• Traditional dosing: 9 week supply at 12.5mg/week, 8 week supply at 15mg/week

• supplied in six 2mL vials at a concentration of 10mg/mL

EXTENDED DOSING PACKAGE | 100mg total

• Available to established patients only

• supplied in five 2mL vials at a concentration of 10mg/mL