Type of Injection: Subcutaneous

Frequency of Injection: Weekly (or as directed by your provider)

Optimal Storage: Refrigeration

BUD: up to 12 months on average

Information on Tirzepatide 

CUSTOMIZABLE DOSING PLAN

Recommended Dosing Schedule for Initiation of Treatment:

2mg once weekly for 2 weeks

4mg once weekly for 4 weeks (you should remain at this dose longer if you are losing weight consistently)

6mg once weekly for 3 weeks

Recommended Dosing Titration:

Increase by 2mg every 3-4 weeks as needed to a maximum dose of 14mg/week. If you have adequate appetite suppression at your current dose, you do not need to continue to increase. If you are sensitive to the medication or are experiencing any side effects, do not increase your dose. If you had sensitivities to the medication during any point of treatment, you can increase by only 1mg at a time if desired.

TRADITIONAL DOSING PLAN

Recommended Dosing Schedule for Initiation of Treatment:

2.5mg once weekly for 4 weeks

5mg once weekly for 4 weeks

Recommended Dosing Titration:

Increase by 2.5mg every 3-4 weeks as needed to a maximum dose of 15mg/week. If you have adequate appetite suppression at your current dose, you do not need to continue to increase. If you are sensitive to the medication or are experiencing any side effects, do not increase your dose. If you had sensitivities to the medication during any point of treatment, you can increase by only 5-10 units at a time if desired.

Below are the units you should administer based on the dose you are trying to achieve. The traditional dosing schedule doses are highlighted in purple.

5 mg/0.5mL Concentration

1mg = 10 units

2mg = 20 units

2.5mg = 25 units

3mg = 30 units

4mg = 40 units

5mg = 50 units

6mg = 60 units

7mg = 70 units

7.5mg = 75 units

8mg = 80 units

9mg = 90 units

10mg = 100 units

11mg = 110 units (1.1mL)

12mg = 120 units (1.2mL)

12.5mg = 125 units (1.25mL)

13mg = 130 units (1.3mL)

14mg = 140 units (1.4mL)

15mg = 150 units  (1.5mL)

TIER 1 | 40mg total

• 9 week supply for those initiating treatment, 10 week supply at 4mg/week

• Traditional Dosing: 8 week supply at 5mg/week

• supplied in two 2mL vials at a concentration of 5mg/0.5mL

TIER 2 | 60mg total

• Custom Dosing: 10 week supply at 6mg/week

• Traditional Dosing: 8 week supply at 7.5mg/week

• supplied in two 3mL vials at a concentration of 5mg/0.5mL

TIER 3 | 80mg total

• Custom Dosing: 10 week supply at 8mg/week, 8 week supply at 10mg/week

• Traditional Dosing: 8 week supply at 10mg/week

• supplied in four 2mL vials at a concentration of 5mg/0.5mL OR in one 2mL vial and two 3mL vials at a concentration of 5mg/0.5mL

TIER 4 | 120mg total

• Custom dosing: 10 week supply at 12mg/week, 8 week supply at 14mg/week

• Traditional dosing: 9 week supply at 12.5mg/week, 8 week supply at 15mg/week

• supplied in four 3mL vials at a concentration of 5mg/0.5mL

EXTENDED TREATMENT PLAN (MID) | 100mg total

• Duration will vary based on your current dosing plan

• supplied in two 2mL and two 3mL vials (for a total of 10mL) at a concentration of 5mg/0.5mL

EXTENDED TREATMENT PLAN (HIGH) | 180mg total

• Duration will vary based on your current dosing plan

• supplied in six 3mL vials at a concentration of 5mg/0.5mL